![]() If you develop bleeding while your INR is too high, it can be life-threatening. If your INR is too high, you’re at increased risk of bleeding. If you’re taking these medications, your target INR range may be between 2 and 3.5. A lower INR means your blood clots more quickly than desired. A normal INR range is 0.8 to 1.1 if you’re not taking anticoagulant medications. When the INR is higher than the recommended range, it means that your blood clots more slowly than desired. In certain situations, such as having a mechanical heart valve, you might need a slightly higher INR. These disorders include atrial fibrillation or a blood clot in the leg or lung. An INR range of 2.0 to 3.0 is generally an effective therapeutic range for people taking warfarin for certain disorders. In healthy people an INR of 1.1 or below is considered normal. This ratio - which allows for easier comparisons of test results from different laboratories - is used if you take blood-thinning medications. A number lower than that range means blood clots more quickly than normal. A number higher than that range means it takes blood longer than usual to clot. The average time range for blood to clot is about 10 to 13 seconds. Prothrombin time test results can be presented in two ways. Home testing kits are available for people who have to take blood thinners for long periods and who have been trained in taking blood samples and testing them. You may receive the test result within minutes, while you are still in the exam room. In some clinics, a nurse will take a sample of your blood with a finger stick. If you are taking warfarin to prevent blood clots, your provider will most likely. If you are not taking blood thinning medicines, such as warfarin, the normal range for your PT results is: 11 to 13.5 seconds. If your provider sends your blood to an off-site laboratory, it may take several days to receive the results. Most of the time, results are given as what is called INR (international normalized ratio). If the laboratory analysis is done on-site, you could have your test results within hours. In a person who is not taking warfarin, the INR would be approximately 1. In most cases the target INR range will be between 2 and 3, although other ranges may be chosen if there are special circumstances. ![]() The target INR range depends upon the clinical situation. Additionally, certain substances affect the prothrombin time and INR when taking Coumadin/warfarin. The longer it takes the blood to clot in the assay, the higher the PT and INR. ![]() The INR should be rounded and reported to. Your blood might be sent to a laboratory for analysis. PT and the PT normal range mean value contain one deci-mal place (e.g., 12.0) and ISI includes two decimal places (e.g., 1.05). Obtaining the blood sample for prothrombin time testing usually takes just a few minutes, like any other blood test. You might experience soreness or minor bruising at the site in the arm where your blood is drawn. 2, 3 However, the single prospective randomized trial on this topic followed 363 patients for two years and found no difference in complications or time spent in the therapeutic range.A prothrombin time test is similar to any other blood test. Two trials using a before-and-after design (which is still more subject to bias than a prospective randomized trial) found more hemorrhages and recurrent thromboembolia in the usual care group than in the group managed by AMS. Large-scale randomized controlled trials with an appropriate duration of follow-up are lacking. When patients can choose whether to attend an AMS or get usual care, it is possible that more motivated, compliant patients are attracted to the AMS. 1 However, most studies were small, and many were non-randomized. A systematic review of the evidence found some support for AMS and PSM over usual care because of increased patient time in the therapeutic range and fewer bleeding complications. ![]() Two alternatives to managing anticoagulation in the primary care office are using anticoagulation management services (AMS) and patient self-monitoring (PSM), which relies on home testing of the INR. ![]()
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